Jay Keasling and Howard Chou of Berkeley Lab and the Joint BioEnergy Institute (JBEI) have invented a fermentation process to produce 5-carbon alcohols from genetically modified E. coli host cells regardless of the feedstock used. This is the first time isopentanol has been synthesized from the...

Alex Zettl and Carolyn Bertozzi of Berkeley Lab are the first to develop a mechanism to introduce molecules into a biological cell without harming the cell itself. The nanoinjector they devised is a single, multi-walled carbon nanotube (CNTs), called a nanoneedle, attached to the tip of an atomic...

Platinum-based anticancer drugs, such as the US approved drugs cisplatin, carboplatin, and oxaliplatin, are among the most active anticancer agents. These platinum compounds are known to bind to DNA and trigger cell cycle arrest and apoptosis of cancer cells. These drugs appear to have similar...

Berkeley Lab researchers have developed technologies to evaluate levels of the long, non-coding RNA to assess the aggressiveness of a cancer and to modulate levels of the long non-coding RNA. This invention addresses the need to identify patients with potentially metastatic tumors versus non-...

Berkeley Lab researchers Gang Ren and Lei Zhang have developed new inhibitors of cholesteryl ester transfer protein (CETP), which has been the focus of research into drugs that regulate levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL), also known respectively as “good” and...

Berkeley Lab researchers including Yasuo Yoshikuni, Gaoyan Wang, Zhiying Zhao, and Jan-Fang Cheng have developed a strategy to chromosomally integrate and express DNA constructs comprising single genes to complex pathways in a broad range of bacterial hosts. By comparing traditional product and...

Ronald Zuckermann and a team of researchers from Berkeley Lab’s Molecular Foundry have developed a simple polymer that significantly accelerates the capture of CO2 in a mineral form suitable for underground storage. The polymer is a low molecular weight peptoid that catalyzes the conversion of CO2...

Thin porous layers are effectively invisible to current seismic methods used for reservoir imaging. Since gas and oil deposits are usually attributed to fluid-saturated porous layers, Gennady Goloshubin and Valeri Korneev have developed an imaging method that provides a more accurate determination...

Researchers at the DOE Joint BioEnergy Institute (JBEI) have developed a technology to preferentially produce and extract sugars produced by the direct acid hydrolysis of biomass from an aqueous solution of ionic liquids such as 1-ethyl-3-methylimidaolium chloride. JBEI researchers have extracted...