Ready for Transfer

Tendon Stem Cells

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Laboratory: National Institute of Dental and Craniofacial Research (NIDCR)

Technology: Tendon stem cells

Opportunity: NIDCR’s Molecular Biology of Bones and Teeth Section is seeking interested parties to join in collaborative research to further develop, evaluate, or commercialize the use of tendon stem cells. 

Details: According to NIDCR, a limited understanding of basic tendon biology has currently stymied the development of new treatment options for injured tendons. Clinicians have reported that tendon injuries are very slow to heal, and the healed tendon pales in comparison to the original when measuring mechanical strength and structural integrity.

The NIDCR tendon stem cell invention relates to a cell-based therapy that uses tendon stem progenitor cells to form tendon structures that can integrate into bones to form enthesis-like structures.

Benefits: This novel stem cell technology can improve the current tendon injury healing treatment and hopefully provide positive treatment outcomes to reduce injury pain and loss of mobility. 

Potential Applications:

  • Treatment of damaged tendons that are slow to repair after injury.
  • May remedy other pathological conditions that are caused by ectopic calcification, such as around artificial heart valves or that develops in the rare inherited disease, Fibrodysplasia Ossificans Progressiva (FOP). 

Contact: For more information about this NIDCR technology, contact Marian Young at myoung@dir.nidcr.nih.gov.

To view the original technology listing on the National Institutes of Health (NIH) website, visit https://www.ott.nih.gov/technology/e-233-2007.