Agency/Department

FLC Region

Security Lab

No

Address

1 Cyclotron Road
Berkeley, CA 94720
United States

(P)

510-486-7727

Description

The BSISB has constructed an infrared beamline at the Advanced Light Source to advance the imaging of living microbes relevant to DOE missions. Synchrotron radiation-based Fourier transform infrared (SR-FTIR) microscopy is a label-free, non-invasive molecular technique that couples the high brightness of synchrotron radiation with the high throughput and vast analytical capabilities of FTIR spectrometers. With a synchrotron source, FTIR microscopes are capable of diffraction-limited chemical imaging with signal-to-noise-ratios 100-1000 times greater than standard blackbody sources. This enhancement of spatial resolution and signal levels enables investigations of sophisticated microbial biochemistry for a broad range of innovative applications.
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