A further enhancement to diffusion MRI technologies is being offered by researchers at NIST. The invention proposes and claims an MRI method that is based on the measurement and acquisition of multiple pulsed field gradient (m-PFG) rather than the previously used single-pulsed field gradient (s-PFG) MRI sequences. In particular, a double PFG (d-PFG) sequence offers higher sensitivity and greater robustness as it is more sensitive to the effect of "restriction", i.e., to water trapped within the axon's intracellular space.
More info: Dr. Uri Reichman, 301-435-4616, UR7a@nih.gov