Laboratory Information:
UCLA - Laboratory of Structural Biology and Molecular Medicine
P.O. Box 951570
Los Angeles, CA 90095-1570
Website: http://www.doe-mbi.ucla.edu/
Agency/Department: Dept. of Energy
Region: Far West
FLC Laboratory Representative:
Dr. David Eisenberg
Phone: 310-825-3754
Fax: 310-206-3914
Email: david@mbi.ucla.edu
Background/History of the Laboratory:
The Laboratory of
Structural Biology and Molecular Medicine is an Organized
Research unit at the University of California, Los Angeles.
Core funding and oversight is provided by the Department of
Energy.
Programs
include:
Collaborative
research with other agencies and organizations is fostered by
the Laboratory.
Mission of the Laboratory:
The missions of
the Laboratory of Structural Biology and Molecular Medicine
are: the partnering of structural and computation biology in
the determination of folds for proteins in genomes, and the
analysis of function and interactions from genome sequences;
and the development of molecular nuclear medicine, including
new diagnostic biological imaging procedures and their
relationship to drug therapies to improve the quality of
life.
Facilities:
Technology Transfer Mechanisms:
- Cooperative Research and Development Agreements (CRADAs)
- Facility Sharing
- Commercial Outreach
- Educational Outreach
- Workshops
- Interaction through Computer Networks
Technology Areas of Expertise:
- Algorithms for inverted and direct protein folding
- Gene expression processes imaging
- Human Genome
- Human subject protection
- Imaging reporter gene expression in vivo
- Merger of PET and MRI into a single imaging technology
- Merging Biology, Biotechnology, and Advanced Imaging Technologies with Drug Design
- Miniaturization of PET technology
- Molecular biology with advanced imaging methods
- Molecular nuclear medicine
- Protein (and RNA and DNA) structures
- X-ray and NMR structural efforts